FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine. In the application described in the medical device and method that implement siRNA. In addition to one or more siRNA constructs, the device includes nanostructures made on the surface to form nanotopografii. It can be made arbitrarily or ordered pattern of structures, such as a complex pattern consisting of structures of different sizes and/or shapes. Microneedles can be introduced into the device. On the surface of the microneedle can be formed by a pattern comprising nanostructures.
EFFECT: group of inventions facilitates the delivery of siRNA.
22 cl, 43 dwg, 5 tbl
