FIELD: medicine.
SUBSTANCE: vaccine contains an immunising rabies antigen having an infectious activity of 6.0-8.5 lg MLD50/ml, natural or synthetic zeolite, and an attractant. A method for producing the vaccine involves preparing an inoculation material of a rabies virus strain, infecting a continuous cell culture with the inoculation material, culturing the virus, collecting the virus-containing fluid followed by producing the immunising rabies antigen added with edible and forming agents, and keeping for 60-90 minutes at room temperature. Zeolite is supposed to have a particle size of 50-500 mcm and to be heat treated at 120-180°C for 2.0-3.0 h; the end product is prepared by extrusion followed by the capillary chemical dewatering of the produced mass at room temperature.
EFFECT: inventions enable producing the end product in an easier and faster way, ensuring longer shelf life and keeping its antigenic and immunogenic activity.
7 cl, 32 ex
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