FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions relates to mouthwash, containing basic amino acid together with a preservative, and to a method of its application. The mouthwash contains a water solution of the basic amino acid - arginine in the free form or in the form of salt in an amount, corresponding to 0.01 to 2 wt % of the total composition weight, where the weight of the basic amino acid is calculated per a free base form, and an effective amount of the preservative, selected from combinations of methylisothiazolinone (MIT) with benzyl alcohol and/or phenoxyethanol and a combination of phenoxyethanol and benzyl alcohol. The presevatives are applied in the following amount: MIT 0.0005-0.03 wt %, benzyl alcohol 0.05-0.25 wt %, phenoxyethanol 0.1-0.7 wt %. The method of reducing or suppressing the formation of dental caries includes the application of an effective amount of the said mouthwash in the oral cavity of the subject requiring it.
EFFECT: application of the said combinations of the preservatives in a combination with arginine provides higher resistance to microbial contamination, in particular to a mould fungus.
9 cl, 1 ex
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Authors
Dates
2015-09-27—Published
2010-11-12—Filed