SYNERGISTIC COMBINATIONS OF CAROTENOIDS AND POLYPHENOLS Russian patent published in 2015 - IPC A61K31/15 A61K31/05 A61K36/00 A61P43/00 

Abstract RU 2563991 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to the pharmaceutical industry, namely to a therapeutic anti-inflammatory composition, which contains one or several polyphenols and two or more carotenoids, which are selected from the group, consisting of lutein, lycopene and β-carotene, where the polyphenols are selected from the group consisting of carnosic acid, quercetin, resveratrol and gallic acid, in a specified quantity; to the method of inhibition or reduction of superoxide-ions formation, NO, TNF-α and/or PGE2 in a subject-mammal, which the said composition is introduced to; to the method of treating pathological conditions, in which superoxide-ions, NO, TNF-α and/or PGE2 function as a modulator or mediator of the said condition of the subject-mammal, which the said composition is introduced to; to the application of a combination of one or several polyphenols and two or more carotenoids, selected from the group, which consists of lutein, lycopene and β-carotene, where the polyphenols are selected from the group, consisting of carnosic acid, quercetin, resveratrol and gallic acid, in a specified quantity.

EFFECT: synergetic interaction of the polyphenol compounds with carotenoids in the inhibition of inflammation pathways is achieved.

28 cl, 11 dwg, 4 ex

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RU 2 563 991 C2

Authors

Zelkkha Morris

Levi Rakhel'

Paran Ehster

Sharoni Joav

Levi Iosef

Dates

2015-09-27Published

2010-01-19Filed