FIELD: chemistry.
SUBSTANCE: invention relates to a novel method of producing intermediate products used to produce NEP inhibitors, particularly NEP inhibitors containing as the backbone chain γ-amino-δ-biphenyl-α-methylalkanoic acid or an ether of said acid, such as ethyl ether of N-(3-carboxy-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methylbutanoic acid or a salt thereof.
EFFECT: novel method of producing intermediate products used to produce NEP inhibitors.
15 cl, 35 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF OBTAINING 5-BIPHENYL-4-AMINO-2-METHYLPENTANOIC ACID | 2008 |
|
RU2530900C2 |
| METHOD AND INTERMEDIATE COMPOUNDS FOR OBTAINING DERIVATIVES OF 5-BIPHENYL-4-YL-2-METHYLPENTANIC ACID | 2009 |
|
RU2513521C2 |
| METHOD AND INTERMEDIATE COMPOUNDS FOR PRODUCING 5-BIPHENYL-4-IL-2-METHYLPENTANIC ACID DERIVATIVES | 2013 |
|
RU2636936C2 |
| SULFUR-CONTAINING COMPOUNDS, METHODS FOR THEIR PREPARING AND PHARMACEUTICAL PREPARATIONS BASED ON THEREOF | 2000 |
|
RU2244708C2 |
| DERIVATIVES OF DOLASTATIN 10 | 2002 |
|
RU2296750C2 |
| DERIVATIVES OF 2-PHENOXY AND 2-PHENYLSULPHONAMIDE WITH CCR3 ANTAGONISTIC ACTIVITY FOR TREATING ASTHMA AND OTHER INFLAMMATORY OR IMMUNOLOGICAL DISEASES | 2004 |
|
RU2380356C2 |
| DERIVATIVES OF DOLASTATIN 10 AND AURISTATINS | 2014 |
|
RU2662951C2 |
| 5-AMINOCYCLYLMETHYLOXAZOLIDIN-2-ONE DERIVATIVES | 2008 |
|
RU2492169C2 |
| NOVEL METHOD FOR OBTAINING INTERMEDIATE COMPOUNDS, APPLIED IN OBTAINING NEP INHIBITORS | 2011 |
|
RU2573824C2 |
| INHIBITORS OF HEPATITIS C VIRUS HAVING RODLIKE CHAIN AND COMPRISING {2-[4-(BIPHENYL-4-YL)-1H-IMIDAZO-2-YL]PYRROLIDIN-1-CARBONYLMETHYL}AMINE FRAGMENT | 2012 |
|
RU2625787C2 |
