PYRROLO[2,3-b]PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS Russian patent published in 2015 - IPC C07C307/02 C07D333/20 

FIELD: chemistry.

SUBSTANCE: invention relates to a compound of formula VIla:

where: R⁸⁴ is selected from a group consisting of hydrogen, C_1-6alkoxy, and -Cl; R⁹², R⁹⁴, R⁹⁵ and R⁹⁶ are independently selected from a group consisting of hydrogen, halogen and fluoro-substituted C_1-6alkyl; R⁹⁹ is selected from a group consisting of C_1-6alkyl, optionally substituted phenyl, thiophene and -NR⁷⁹R⁸⁰, where the phenyl substitutes are selected from halogen and fluoro-substituted C_1-6alkyl; and R⁷⁹ and R⁸⁰ are independently hydrogen or C_1-6alkyl, or R⁷⁹ and R⁸⁰ are combined with a nitrogen atom with which they are bonded to form a 5-7-member heterocycloalkyl in which 1-3 carbon atoms are substituted with O, S or N heteroatoms.

EFFECT: said compounds are active with respect to protein kinase.

25 cl, 2 tbl, 59 ex