COMPOUNDS SUITABLE FOR CANCER TREATMENT Russian patent published in 2015 - IPC C07D401/12 C07D403/12 C07D215/04 C07D215/18 C07D215/24 C07D241/42 A61K31/4427 A61K31/4709 A61K31/497 A61K31/498 A61K31/506 A61P35/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to application of formula

compound,

where stands for aromatic ring, where V represents C or N and, where V represents N, V is in meta- or para-position to Z, R independently represents hydrogen atom, halogen atom or group, selected from group -CN, hydroxyl group, group -COOR₁, (C₁-C₃)fluoroalkyl group, (C₁-C₃)fluoroalkoxy group, group -NO₂, group -NR₁R₂, (C₁-C₄)alkoxy group, phenoxy group and (C₁-C₃)alkyl group, where said alkyl is possibly monosubstituted with hydroxyl group, R₁ and R₂ independently represent hydrogen atom or (C₁-C₃)alkyl group, n equals 1, 2 or 3, n' equals 1 or 2, R' represents hydrogen atom, halogen atom or group, selected from (C₁-C₃)alkyl group, group -NO₂, group -NR₁R₂, morpholinyl group, N-methylpiperazinyl group, (C₁-C₃)fluoroalkyl group and (C₁-C₄)alkoxy group, R" represents hydrogen atom, Z, Y, X, W, T, U independently represent N or C, and where maximum four of groups V, T, U, Z, Y, X and W represent N, and at least one of groups T, U, Y, X and W represents N, or any of its pharmaceutically acceptable salts for obtaining medication for prevention, inhibition or treatment of cancer. Invention also relates to application of particular compounds, to novel quinoline and isoquinoline derivatives, pharmaceutical composition based on novel quinoline and isoquinoline derivatives.

EFFECT: obtained are novel quinoline and isoquinoline derivatives, and novel biological activity of known compounds is discovered.

10 cl, 2 tbl, 6 ex