FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to a method for producing (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluor-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane carboxamide (compound I) effective in treating CFTR-mediated diseases, such as cystic fibrosis, as well as to methods for producing intermediate compounds. 
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EFFECT: producing the compounds effective for treating CFTR-mediated compounds, such as cystic fibrosis.
62 cl, 2 tbl
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