FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to paediatric traumatology, and can be used for treating fractures in the children suffering a multisystem injury. The optimal time of osteosynthesis is determined by measuring during the first post-injury hours the blood serum concentrations of S100 protein and cystatin C markers: the reference concentrations of S100 protein 312.2-587.8 ng/l and cystatin C 832.8-1062 ng/ml followed by a two-fold or higher increase for 1-4 days show manifestations of severe cerebral and renal metabolic disturbances; a general therapy is optimised, and a delayed osteosynthesis is performed at least 5-7 days later; the reference concentrations of S100 protein 103.8-292.0 ng/l and cystatin C 541-967 ng/ml followed by at least two-fold increase or decrease during the 1st and following days show reversible functional cerebral and renal metabolic disturbances, whereas the 1st-4th post-injury day is considered to be the optimal time for osteosynthesis.
EFFECT: using the method enables detecting latent organ failures, assessing a degree of severity and performing the osteosynthesis as soon as reasonable that is expected to increase the clinical effectiveness in the concomitant and multisystem injury in the children.
4 tbl, 8 dwg, 3 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD OF EARLY DIAGNOSTICS OF FAT EMBOLISM SYNDROME IN CASE OF FRACTURES OF LONG TUBULAR BONES AND PELVIS BONES | 2013 |
|
RU2545805C2 |
METHOD FOR PREDICTING THE COURSE OF POSTTRAUMATIC PERIOD IN CASES OF MULTIPLE TRAUMA OF LOCOMOTOR SYSTEM | 1995 |
|
RU2151398C1 |
METHOD FOR FAT EMBOLISM SYNDROME DIAGNOSIS IN CASE OF LOWER LIMB BONE FRACTURES | 2016 |
|
RU2611363C1 |
METHOD FOR INTENSIVE THERAPY OF MULTIPLE ORGAN FAILURE IN PATIENTS WITH POLYTRAUMA | 2013 |
|
RU2523452C1 |
METHOD FOR EVALUATING PATIENT DISEASE SEVERITY IN ACUTE MULTIPLE TRAUMA PERIOD | 2000 |
|
RU2181488C1 |
METHOD FOR PREDICTION OF CLINICAL OUTCOME OF TRAUMATIC DISEASE ACUITY OF ELDERLY AND SENILE PATIENTS WITH SEVERE COMBINED INJURY | 2015 |
|
RU2613317C2 |
METHOD OF PREVENTIVE THERAPY OF RHINAL COMPLICATIONS AFTER NOSE TRAUMA | 2013 |
|
RU2559587C2 |
METHOD FOR PREDICTION OF THROMBOEMBOLIC COMPLICATIONS IN PATIENTS WITH POLYTRAUMA | 2018 |
|
RU2699050C1 |
PREVENTIVE METHOD OF SUPPURATIVE-SEPTIC COMPLICATIONS CASUED BY SEVERE COMBINED INJURY | 2006 |
|
RU2326687C1 |
METHOD OF TREATING PATIENTS WITH COMBINED CRANIOCEREBRAL INJURY | 2010 |
|
RU2446834C2 |
Authors
Dates
2015-11-27—Published
2014-03-05—Filed