ANTIBODIES AGAINST NEYROPILIN AND METHODS OF THEIR APPLICATION Russian patent published in 2015 - IPC C07K16/28 

FIELD: biotechnologies.

SUBSTANCE: group of inventions is offered which describes the extracted antibody or its fragment linking with neuropilin 1 (variants), the method of obtaining of the antibody or its fragment, the extracted nucleinic acid coding the named antibody or its fragment, the host cell for expression of the named antibody or its fragment, the immunoconjugate containing the antibody or its fragment, the method of neuropilin 1 detection. In one version the antibody contains HVR-H1 with the amino-acid sequence SEQ ID NO: 3, HVR-H2 with SEQ ID NO: 4, HVR-H3 with SEQ ID NO: 5, HVR-L1 with SEQ ID NO: 8, HVR-L2 with SEQ ID NO: 9, and HVR-L3 with SEQ ID NO: 10. In another version the antibody contains the sequences VH SEQ ID NO: 2 and VL SEQ ID NO: 7.

EFFECT: invention expands the arsenal of antibodies linking with neuropilin.

12 cl, 2 dwg, 1 tbl, 2 ex