FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to biotechnology. There are presented methods for producing a polymer containing fucosa, the same polymer containing fucosa and uses thereof. The polymer is produced by Enterobacter DSM 23139 bacterial culture in one version with using glycerol or glycerol-rich mixtures as a carbon source. According to another version, the carbon source represents food or industrial waste containing one or more compounds, such as sugar, alcohol, organic acid, alkane. During the charge phase, the bacteria are cultured in a bioreactor, mixed and aerated in a medium containing the carbon source including glycerol, a nitrogen source and non-organic salts. The feeding phase involves culturing the bacteria with the carbon source, and in the nitrogen-free environment. The polymer is applicable as an anti-cancer or anti-inflammatory agent, as a moisturising or anti-age additive, as well as for producing biodegradable composite films or microspheres for controlled released of medicinal products.
EFFECT: produced polymer has the flocculating and emulsifying activity and is applicable as a gelling material.
25 cl, 3 dwg, 4 tbl, 4 ex
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Authors
Dates
2016-01-20—Published
2010-12-10—Filed