FIELD: chemistry.
SUBSTANCE: invention relates to field of biochemistry, in particular to hypoallergenic polypeptide of Grass family. Also disclosed are DNA molecule, which codes said hypoallergenic polypeptide, recombinant expression vector, containing said DNA molecule, and host cell, transformed by means of said DNA molecule or said vector, for obtaining said hypoallergenic polypeptide. Disclosed are method for obtaining said hypoallergenic polypeptide, application of said hypoallergenic polypeptide or said DNA molecule for obtaining medication and pharmaceutical preparation for prevention or treatment of type 1 allergies, which contains efficient quantity of hypoallergenic polypeptide.
EFFECT: invention makes it possible to efficiently treat type 1 allergies.
14 cl, 8 tbl, 9 ex, 24 dwg
Title | Year | Author | Number |
---|---|---|---|
VARIANTS OF GROUP 5 ALLERGENS OF CEREALS WITH REDUCED ALLERGENICITY DUE TO MUTAGENESIS OF PROLINE RESIDUES | 2010 |
|
RU2658767C1 |
MODIFICATION OF GROUP 6 POACEAE (BLUEGRASS) ALLERGENS WITH LOW ALLERGENIC CAPACITY DUE TO MUTAGENESIS OF PROLINE RESIDUES | 2010 |
|
RU2607373C2 |
DNA SEQUENCE AND PRODUCTION OF GRASS POLLEN ALLERGEN Phi p4 USING RECONBINANT METHODS | 2003 |
|
RU2327739C2 |
VARIANTS OF PRINCIPAL ALLERGEN Phl p 1 FROM TIMOTHY GRASS (PHLEUM PRATENSE) | 2003 |
|
RU2323942C2 |
PhI p 5a DERIVATIVES HAVING DECREASED ALLERGENIC CAPACITY AND RETAINED T-CELLULAR REACTIVITY | 2004 |
|
RU2368620C2 |
HYBRID PEPTIDE CARRYING PROTEINS AS VACCINES AGAINST ALLERGY | 2012 |
|
RU2630652C2 |
VERSION OF GROUP I Poaceae ALLERGEN CHARACTERISED BY LOWER ALLERGENICITY AND MAINTAINED T-CELL RESPONSIVENESS (VERSIONS), CODING DNA MOLECULE AND APPLICATION THEREOF | 2005 |
|
RU2409589C2 |
DNA SEQUENCE AND RECOMBINANT PRODUCTION OF MAIN ALLERGENS OF GROUP 4 FROM POACEAE | 2004 |
|
RU2373283C2 |
NEW MUTANT ALLERGENS | 2001 |
|
RU2285042C2 |
DNA SEQUENCE AND PREPARING CEREAL CROPS ALLERGEN BY RECOMBINANT METHOD | 2000 |
|
RU2238321C2 |
Authors
Dates
2016-02-20—Published
2010-12-17—Filed