VERSIONS OF GROUP OF 5 ALLERGENS OF TRUE GRASSES WITH REDUCED ALLERGENICITY RESULTING FROM MUTAGENESIS OF PROLINE RESIDUES Russian patent published in 2016 - IPC C07K14/415 C12N15/70 C12N15/29 C12R1/19 A61K39/36 A61P37/08 

Abstract RU 2575606 C2

FIELD: chemistry.

SUBSTANCE: invention relates to field of biochemistry, in particular to hypoallergenic polypeptide of Grass family. Also disclosed are DNA molecule, which codes said hypoallergenic polypeptide, recombinant expression vector, containing said DNA molecule, and host cell, transformed by means of said DNA molecule or said vector, for obtaining said hypoallergenic polypeptide. Disclosed are method for obtaining said hypoallergenic polypeptide, application of said hypoallergenic polypeptide or said DNA molecule for obtaining medication and pharmaceutical preparation for prevention or treatment of type 1 allergies, which contains efficient quantity of hypoallergenic polypeptide.

EFFECT: invention makes it possible to efficiently treat type 1 allergies.

14 cl, 8 tbl, 9 ex, 24 dwg

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RU 2 575 606 C2

Authors

Martin Val'D

Andreas Nandi

Khel'Mut Fibig

Bernkhard Veber

Khel'Ga Kalert

Geral'D Reze

Oliver Kromvell'

Dates

2016-02-20Published

2010-12-17Filed