FIELD: genetic engineering.
SUBSTANCE: provides genetic sequence of grass pollen main allergen Phi p 4. Fragments of this sequence, combinations of its partial sequences and point mutants have hypoallergenic action. Recombinant molecules of DNA and derivative polypeptides, fragments, new combination of partial sequences and versions can be applied for treatment of diseases associated with grass pollen allergy.
EFFECT: proteins produced by recombinant methods can be applied for diagnostics of grass pollen allergosis.
16 cl, 8 dwg, 6 tbl
