FIELD: chemistry.
SUBSTANCE: group of inventions discloses a method of producing carbamylated darbepoetin 9C-DEPO, which is carbamylated on all amino acid residues of lysine which are part of a darbepoetin molecule, containing a carbamylated amino acid residue of alanine in the N-terminal region of said protein, which includes carbamylation of darbepoetin in the presence of cyanates, as well as a medicinal agent which includes carbamylated darbepoetin 9C-DEPO.
EFFECT: group of inventions has marked cytoprotective action.
2 cl, 3 dwg, 3 ex
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Authors
Dates
2016-02-20—Published
2013-07-09—Filed