FIELD: biotechnology.
SUBSTANCE: invention relates to the recombinant production of human proteins, and can be used to produce recombinant human erythropoietin. As a producer of recombinant highly sialylated human erythropoietin, a strain of Chinese hamster ovary cells CHO-EPO 4A9 deposited with number RKKK(P) 767 D is used.
EFFECT: recombinant erythropoietin produced by this producer strain is characterized by a high degree of sialification, which allows to significantly increase the yield of the target product in the production of erythropoietin substance.
1 cl, 1 dwg, 2 tbl, 2 ex
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