FIELD: chemistry.
SUBSTANCE: invention relates to obtaining tetravalent neoglycoconjugates with carbonhydrate branching core and derivative of L-glutamic acid in hydrophobic block, suitable for preparation of liposomes, of formula . Method includes conjugation of azidoethyl carbonhydrate derivative, selected from 1-O-(2-azidoethyl)-α-D-mannopyranozide or 1-O-(2-azidoethyl)lactoside, with bishexadecyl-N-({3-[N'-2,3,4,6-tetra-O-propynyl-β-D-glycopyranozyloxy]-carbamoyl}-propyonyl)-L-glutamate.
EFFECT: increase of affinity of carbohydrate residuals to receptors, effective method of thereof obtaining.
2 cl, 1 dwg, 8 ex
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Authors
Dates
2016-02-27—Published
2014-11-06—Filed