FIELD: biotechnology.
SUBSTANCE: group of inventions is described, including double-stranded oligo-RNA structure for efficient delivery of RNA, and a method of its manufacturing, a nanoparticle containing the above-mentioned double-stranded oligo-RNA structure, a method of controlling the gene expression in vitro by use of the above-mentioned oligo-RNA structure, and a method of controlling the gene expression in vivo by use of the above-mentioned nanoparticle.
EFFECT: invention expands the range of means of delivery of RNA to the cells of the body.
28 cl, 5 dwg, 1 tbl, 4 ex
| Title |
Year |
Author |
Number |
| IMPROVED NANOPARTICLE TYPE OLIGONUCLEOTIDE STRUCTURE HAVING HIGH EFFICIENCY AND METHOD FOR PREPARING SAME |
2014 |
- Pak Khan O
- Chkhe Chejuk
- Yun Pen O
- Khan Boram
- Chkhve Ki-Yn
- Ko Yunkho
- Kvon Tkheu
- Li Che Ton
- Kim Sun Gi
|
RU2670164C2 |
| NEW OLIGONUCLEOTIDES CONJUGATES AND USE THEREOF |
2012 |
- Chkhe Chejuk
- Khan Boram
- Kim Khan-Na
- Pak Khan O
- Yun Pen O
- Kim Sun Gi
- Chon Kvan-Chu
- Kvon Tkheu
- Chkhve Chon Dok
- Li Sam Yun
- Chon Yn-Chun
|
RU2599449C1 |
| GEN-SPECIFIC SIRNA RELATED TO RESPIRATORY DISEASE, TWO-SPIRAL CONSTRUCT OF OLIGO-RNA COMPRISING SIRNA, AND CONTAINING IT COMPOSITION FOR PREVENTION OR TREATMENT OF RESPIRATORY DISEASE |
2014 |
- Chkhe Chejuk
- Pak Khan O
- Yun Pen O
- Khan Boram
- Kim Mi Na
|
RU2656154C2 |
| AMPHIREGULIN GENE-SPECIFIC DOUBLE-STRANDED OLIGONUCLEOTIDES AND COMPOSITIONS CONTAINING THEM FOR THE PREVENTION AND TREATMENT OF FIBROSIS-RELATED DISEASES AND RESPIRATORY DISEASES |
2019 |
- Kim, Tae-Rim
- Yoon, Pyoung Oh
- Ko, Youngho
- Bae, Seon Joo
- Park, Han-Oh
- Son, Seung Seob
- Jun-Hong, Park
- Yun, Sung Il
|
RU2795179C2 |
| COMPOSITION FOR PREVENTION OR TREATMENT OF DISEASE ASSOCIATED WITH OBESITY, CONTAINING AMPHIREGULIN-SPECIFIC DOUBLE-CHAIN OLIGONUCLEOTIDE STRUCTURE |
2021 |
- Park, Jun Hong
- Park, Han-Oh
- Yun, Sung Il
- Kim, Tae Rim
- Hwang, Soo Hyun
- Song, Kang
- Jung, Sang Hyuk
- Kim, Jangseon
- Lee, Mi Sun
- Choi, Soonja
- Son, Seung-Seob
|
RU2810514C1 |
| DOUBLE-CHAINED OLIGONUCLEOTIDE SPECIFIC TO CTGF GENE AND COMPOSITION CONTAINING IT FOR PREVENTION AND TREATMENT OF FIBROUS DISEASES AND DISEASES ASSOCIATED WITH RESPIRATORY SYSTEM |
2020 |
- Park, Han-Oh
- Kim, Tae-Rim
- Ko, Young-Ho
- Yun, Sung Il
- Park, Jun Hong
|
RU2807108C1 |
| SIRNA CONJUGATE AND METHOD FOR PRODUCING IT |
2010 |
- Khan, Bo Ram
- Park, Khan Okh
- Shin, Mi Sik
- Li, Sam Joung
|
RU2558258C2 |
| SIRNA CONJUGATE AND PREPARATION METHOD THEREOF |
2013 |
- Khan Bo Ram
- Park Khan Okh
- Shin Mi Sik
- Li Sam Jung
|
RU2571218C2 |
| COMPOSITION FOR REDUCING HAIR GRAYING, STIMULATING HAIR GROWTH AND/OR PREVENTING OR REDUCING HAIR LOSS, CONTAINING DOUBLE-STRANDED MCRNA AS ACTIVE INGREDIENT |
2022 |
- Park, Han-Oh
- Lee, Sang-Kyu
- Kwon, Oh Seung
- Goh, Eun-Ah
|
RU2823325C1 |
| DOUBLE-STRANDED OLIGONUCLEOTIDE STRUCTURES CONTAINING AN ANDROGEN RECEPTOR-SPECIFIC SEQUENCE, AND COMPOSITIONS FOR PREVENTING HAIR LOSS AND ENHANCING HAIR GROWTH CONTAINING SAID STRUCTURES |
2019 |
- Park, Han-Oh
- Yun, Sung Il
- Byun, Sang-Jin
- Lee, Myeong-Mi
- Yang, Seung Ya
|
RU2778086C1 |
