AMPHIREGULIN GENE-SPECIFIC DOUBLE-STRANDED OLIGONUCLEOTIDES AND COMPOSITIONS CONTAINING THEM FOR THE PREVENTION AND TREATMENT OF FIBROSIS-RELATED DISEASES AND RESPIRATORY DISEASES Russian patent published in 2023 - IPC C12N15/113 A61K31/713 A61P11/00 A61P11/06 A61P29/00 

Abstract RU 2795179 C2

FIELD: biotechnology.

SUBSTANCE: new amphiregulin-specific oligonucleotide constructs, applied in medicine. The invention discloses double-stranded oligonucleotides capable of inhibiting amphiregulin expression very specifically and effectively.

EFFECT: prevention or treatment of pathological proliferation of connective tissue that accompanies various fibroses, including those that occur as a complication of respiratory diseases.

18 cl, 11 dwg, 13 tbl, 9 ex

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RU 2 795 179 C2

Authors

Kim, Tae-Rim

Yoon, Pyoung Oh

Ko, Youngho

Bae, Seon Joo

Park, Han-Oh

Son, Seung Seob

Jun-Hong, Park

Yun, Sung Il

Dates

2023-05-02Published

2019-05-22Filed