FIELD: biotechnology.
SUBSTANCE: new amphiregulin-specific oligonucleotide constructs, applied in medicine. The invention discloses double-stranded oligonucleotides capable of inhibiting amphiregulin expression very specifically and effectively.
EFFECT: prevention or treatment of pathological proliferation of connective tissue that accompanies various fibroses, including those that occur as a complication of respiratory diseases.
18 cl, 11 dwg, 13 tbl, 9 ex
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