FIELD: chemistry.
SUBSTANCE: invention relates to novel compounds of pyrazole class. Described are methyl 5-(arylcarbamoyl)-1-(benzyl, phenyl)-4-cinnamoyl-1H-pyrazole-3-carboxylates (IIIa-e) having formula shown below, and a method for production thereof.
EFFECT: technical result is providing novel compounds which may be used as precursors for synthesis of novel heterocyclic systems in pharmacology as having analgesic activity.
5 cl, 1 tbl, 3 ex
| Title |
Year |
Author |
Number |
| METHYL 1-ARYL-3-HYDROXY-3'-METHYL-2,4,5'-TRIOXO-6-PHENYL-2,4,5,6-TETRAHYDRO-5'H-SPIRO[INDOLE-7,4'-ISOXAZOLE]-7a(1H)-CARBOXYLATES, METHYL 1-ARYL-(1'-PHENYL AND 1'-BENZYL)-3-HYDROXY-3'-METHYL-2,4,5'-TRIOXO-6-PHENYL-1',2,4,5,5',6-HEXAHYDROSPIRO[INDOLE-7,4'-PYRAZOLE]-7a(1H)-CARBOXYLATES AND METHYL 1'-ARYL-3'-HYDROXY-1,2',3,4'-TETRAOXO-6'-PHENYL-1,2',3,4',5',6'-HEXAHYDROSPIRO[INDENE-2,7'-INDOLE]-7a'(1'H)-CARBOXYLATES, DEMONSTRATING ANALGESIC ACTIVITY AND METHOD FOR OBTAINING THEREOF |
2014 |
- Silajchev Pavel Sergeevich
- Filimonov Valerij Olegovich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
|
RU2577528C2 |
| METHYL 3-METHYL-5-[2-(4-ARYLAMINO)-2-OXOACETYL]-1,6-DIPHENYL-1H-PYRAZOLO[3,4-b]PYRIDINE-4-CARBOXYLATES AND METHYL 3-METHYL-5-[2-(4-ARYLAMINO)-2-OXOACETYL]-6-STYRYL-1-PHENYL-1H-PYRAZOLO[3,4-b]PYRIDINE-4-CARBOXYLATES AND METHOD FOR PREPARING THEM |
2012 |
- Maslivets Andrej Nikolaevich
- Bubnov Nikolaj Vladimirovich
- Silajchev Pavel Sergeevich
- Filimonov Valerij Olegovich
- Makhmudov Ramiz Ragibovich
|
RU2495039C1 |
| 1'-ARYL-4'-HYDROXY-3'-CYNNAMOYL-2H,4H-SPIRO[FURO[3,2-c]CHROMEN-3,2'-PYRROL]-2,4,5'(1'H)-TRIONES EXHIBITING ANALGESIC ACTIVITY, AND METHOD FOR PRODUCING THEM |
2014 |
- Silajchev Pavel Sergeevich
- Filimonov Valerij Olegovich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
|
RU2577523C2 |
| METHOD OF PRODUCING METHYL 7-ARYLCARBAMOYL-6-BENZOYL-2-METHYL-3-PHENYLPYRAZOLO-[1,5-a]PYRIMIDINE-5-CARBOXYLATES |
2009 |
- Maslivets Andrej Nikolaevich
- Denislamova Ekaterina Sergeevna
- Aliev Zajnutdin Gasanovich
|
RU2421455C2 |
| ETHYL 5-ALKYL-7,7-DIMETHYL-2',9,11-TRIOXO-5'-PHENYL-1',2',5,6,7,8,9,11-OCTAHYDROSPIRO{INDENO[1,2-b][QUIOLINE-10,3'-PYRROL}-4'-CARBOXYLATES AND METHOD FOR PREPARING THEM |
2012 |
- Dmitriev Maksim Viktorovich
- Silajchev Pavel Sergeevich
- Makhmudov Ramiz Ragibovich
- Maslivets Andrej Nikolaevich
|
RU2485120C1 |
| 1'-ARYL-1-BENZYL-4'-HYDROXY-6,6-DIMETHYL-3'-CINNAMOYL-6,7-DIHYDROSPIRO[INDOLE-3,2'-PYRROLE]-2,4,5'(1H,1'H,5H)-TRIONES AND 1,1'-DIARYL-4'-HYDROXY-6,6-DIMETHYL-3'-CINNAMOYL-6,7-DIHYDROSPIRO[INDOLE-3,2'-PYRROLE]-2,4,5'(1H,1',5H)-TRIONES, EXHIBITING ANALGESIC ACTIVITY, AND METHOD FOR PRODUCTION THEREOF |
2012 |
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
- Filimonov Valerij Olegovich
- Makhmudov Ramiz Ragibovich
|
RU2520005C2 |
| METHOD OF PRODUCING METHYL 1,7-DIARYL-9-AROYL-4-BENZOYL-3-HYDROXY-2,6-DIOXO-1,7-DIAZASPIRO[4,4]NONE-3,8-DIENE-8-CARBOXYLATES, EXHIBITING ANALGESIC ACTIVITY |
2013 |
- Denislamova Ekaterina Sergeevna
- Dubovtsev Aleksej Jur'Evich
- Makhmudov Ramiz Ragibovich
- Maslivets Andrej Nikolaevich
|
RU2537999C1 |
| ETHYL 3',7-DIOXO-5'-PHENYL-1,6-DIHYDRO-1'H-SPIRO{INDENO[1,2-b]QUINOLINE-6,3'-PYRROLE}-4'-CARBOXYLATES AND SYNTHESIS METHOD THEREOF |
2010 |
- Dmitriev Maksim Viktorovich
- Makhmudov Ramiz Ragibovich
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
|
RU2453549C1 |
| 2-(6-ARYL-4-AROYL-3-METHYL-1-PHENYL-1H-PYRAZOLO[3,4-b]PYRIDIN-5-YL)-2-OXO-N-ARYLACETAMIDES AND METHODS FOR PRODUCTION THEREOF |
2012 |
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
|
RU2501800C2 |
| (Z)-1'-R-6',6'-DIMETHYL-3-(PHENYL(ARYLAMINO)METHYLENE)-6',7'-DIHYDRO-3H-SPIRO[FURANE-2,3'-INDOL]-2',4,4',5(1'H,5'H)TETRAONS AND METHOD OF THEIR OBTAINING |
2008 |
- Maslivets Andrej Nikolaevich
- Silajchev Pavel Sergeevich
- Aliev Zajnutdin Gasanovich
|
RU2365592C1 |
