FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to the new individual compounds of 1'-aryl-4'-hydroxy-3'-cynnamoyl-2H,4H-spiro[furo[3,2-c]chromen-3,2'-pyrrol]-2,4,5'(1'H)-triones of formula (IIIa-c) 
wherein Ar = Ph (a), C6H4Me-4 (b), C6H4OMe-4 (b), which are applicable as primary products for synthesis of new heterocyclic systems and in pharmacology as those exhibiting analgesic activity, and to a method for producing them.
EFFECT: producing new compounds with analgesic activity.
5 cl, 1 tbl, 3 ex
| Title |
Year |
Author |
Number |
| 1'-ARYL-1-BENZYL-4'-HYDROXY-6,6-DIMETHYL-3'-CINNAMOYL-6,7-DIHYDROSPIRO[INDOLE-3,2'-PYRROLE]-2,4,5'(1H,1'H,5H)-TRIONES AND 1,1'-DIARYL-4'-HYDROXY-6,6-DIMETHYL-3'-CINNAMOYL-6,7-DIHYDROSPIRO[INDOLE-3,2'-PYRROLE]-2,4,5'(1H,1',5H)-TRIONES, EXHIBITING ANALGESIC ACTIVITY, AND METHOD FOR PRODUCTION THEREOF |
2012 |
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
- Filimonov Valerij Olegovich
- Makhmudov Ramiz Ragibovich
|
RU2520005C2 |
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2011 |
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- Makhmudov Ramiz Ragibovich
- Maslivets Andrej Nikolaevich
|
RU2467011C1 |
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2014 |
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|
RU2577528C2 |
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2014 |
- Silajchev Pavel Sergeevich
- Filimonov Valerij Olegovich
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- Makhmudov Ramiz Ragibovich
|
RU2583158C2 |
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2012 |
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|
RU2502738C2 |
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2010 |
- Maslivets Andrej Nikolaevich
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|
RU2435777C1 |
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2012 |
- Maslivets Andrej Nikolaevich
- Bubnov Nikolaj Vladimirovich
- Silajchev Pavel Sergeevich
- Filimonov Valerij Olegovich
- Makhmudov Ramiz Ragibovich
|
RU2495039C1 |
| ANALGESIC MEDICATION |
2007 |
- Racheva Nadezhda L'Vovna
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- Fedorovtseva Anastasija Nikolaevna
|
RU2360914C1 |
| 3'-AROYL-1-BENZYL-4'-HYDROXY-1'-(2-HYDROXYETHYL)-6,6-DIMETHYL-6,7-DIHYDROSPIRO[INDOLO-3,2'-PYRROLE]-2,4,5'(1H,1'H,5H)-TRIONES POSSESSING ANALGESIC ACTIVITY AND A METHOD FOR THEIR PREPARATION |
2018 |
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|
RU2688931C1 |
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2014 |
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RU2564440C1 |
