Show metadata Hide metadata

(19)

(11)

2 585 120

(13)

(51)

IPC

G01N33/48(2006-01-01)

G01N33/50(2006-01-01)

(21) (22)

Application

2014137510/15, 2014-09-16

(24)

Start date

2014-09-16

(22)

Actual filing date

2014-09-16

(45)

Published

2016-05-27

(72)

Inventor

Khanokh Elena VladimirovnaRozhdestvenskij Aleksej SergeevichDelov Roman Andreevich

(73)

Holder

Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Professionalnogo Obrazovaniya Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhraneniya Rossijskoj Federatsii Vpo Omgmu Minzdrava Rossii)

METHOD FOR PREDICTION OF CLINICAL COURSE OF MULTIPLE SCLEROSIS Russian patent published in 2016 - IPC G01N33/48 G01N33/50

Abstract RU 2585120 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine and represents method for prediction of clinical course of multiple sclerosis (MS) by blood examination, differing by fact that from blood taken from vein leukocytic suspension is selected, then from leukocyte suspension DNA is recovered and by PCR in real time, presence or absence of pathological alleles in polymorphous variants of genes rs1800629 (TNFα) and rs6074022 (CD40) is determined, wherein if observing allele G of polymorphic locus rs1800629 (TNFα) and allele C of polymorphic locus rs6074022 (CD40) shows high average speed of progression of multiple sclerosis.

EFFECT: invention implementation enables more accurate prediction that promotes selecting corresponding strategy of treatment.

3 cl, 1 tbl, 2 ex

Similar patents RU2585120C2

Title	Year	Author	Number
METHOD FOR PREDICTION OF RISK OF DEVELOPING ISCHEMIC STROKE	2018	Churnosov Mikhail Ivanovich Moskalenko Mariya Ivanovna Milanova Snezhana Nikolovna Ponomarenko Irina Vasilevna Polonikov Aleksej Valerevich	RU2685859C1
METHOD OF PREDICTING SEVERE PRE-ECLAMPSIA	2014	Churnosov Mikhail Ivanovich Kaganovich Evgeniya Nikolaevna Dobrodomova Irina Sergeevna Orlova Valentina Semenovna Polonikov Aleksej Valerevich Proshchaev Kirill Ivanovich	RU2568892C1
METHOD OF PREDICTING DEVELOPMENT OF PRE-ECLAMPSIA IN WOMEN WITH NON-BURDENED HEREDITY	2014	Churnosov Mikhail Ivanovich Kaganovich Evgeniya Nikolaevna Dobrodomova Irina Sergeevna Sobyanin Fedor Ivanovich Sorokina Inna Nikolaevna Polonikov Aleksej Valerevich	RU2568893C1
METHOD OF PREDICTING RISK OF DEVELOPING ISCHEMIC STROKE IN SMOKING WOMEN IN POPULATION OF CENTRAL RUSSIA BASED ON GENOTYPING OF RS11682567 (G>A) POLYMORPHISM OF HSPA8 GENE	2023	Bushueva Olga Iurevna Polonikov Aleksei Valerevich	RU2806497C1
METHOD FOR PREDICTING RISK OF DEVELOPING ISCHEMIC STROKE IN SMOKERS IN POPULATION OF CENTRAL RUSSIA BASED ON GENOTYPING OF RS11682567 (T>G) POLYMORPHISM OF HSPD1 GENE	2023	Bushueva Olga Iurevna Gurtovoi Denis Evgenevich	RU2805392C1
METHOD FOR PREDICTING RISK OF DEVELOPING CHRONIC TRUE ECZEMA IN INDIVIDUALS DEPENDING ON AVAILABILITY OF FAMILY HISTORY	2014	Krikun Evgenij Nikolaevich Churnosov Mikhail Ivanovich Rudykh Natalya Aleksandrovna Denisova Yana Evgenevna	RU2585382C1
METHOD FOR PREDICTION OF RESPIRATORY FAILURE IN PATIENTS WITH BRONCHIAL ASTHMA	2017	Mukhammadieva Guzel Fanisovna Karimov Denis Olegovich Kutlina Tatyana Georgievna Valova Yana Valerevna Bakirov Akhat Barievich Shagalina Alfiya Uzbekovna Idiyatullina Elvira Filaretovna	RU2639122C1
METHOD FOR PREDICTING RISK OF DEVELOPING CHRONIC TRUE ECZEMA IN WOMEN, TAKING INTO ACCOUNT GENETIC FACTORS	2021	Churnosov Mikhail Ivanovich Elykova Anna Vladimirovna Ponomarenko Irina Vasilevna Belyaeva Tatyana Mikhajlovna	RU2753274C1
METHOD FOR PREDICTION OF MODERATE SEVERITY OF CHRONIC TRUE ECZEMA	2014	Denisova Yana Evgenevna Krikun Evgenij Nikolaevich Ovcharova Veronika Sergeevna Churnosov Mikhail Ivanovich	RU2578441C1
METHOD FOR PREDICTING RISK OF STAGE III HYPERTENSIVE DISEASE	2014	Churnosov Mikhail Ivanovich Milanova Snezhana Nikolovna Polonikov Aleksej Valerevich Sorokina Inna Nikolaevna Krivoshej Irina Vasilevna	RU2565407C1

RU 2 585 120 C2

Authors

Khanokh Elena Vladimirovna

Rozhdestvenskij Aleksej Sergeevich

Delov Roman Andreevich

Dates

2016-05-27—Published

2014-09-16—Filed