METHOD OF PREDICTING RISK OF DEVELOPING ISCHEMIC STROKE IN SMOKING WOMEN IN POPULATION OF CENTRAL RUSSIA BASED ON GENOTYPING OF RS11682567 (G>A) POLYMORPHISM OF HSPA8 GENE Russian patent published in 2023 - IPC G01N33/50 C12Q1/6806 C12Q1/6827 C12Q1/686 C12Q1/6876 C12Q1/6883 

Abstract RU 2806497 C1

FIELD: medicine; medical diagnostics.

SUBSTANCE: invention can be used to predict the risk of developing ischemic stroke in smoking women that live in the Central Russia. A venous blood sample is collected. After DNA extraction, genotyping of rs1136141 (G>A) polymorphic variant of the heat shock protein family A gene HSPA8 is performed. If rs1136141-A allele is detected, an increased risk of ischemic stroke is predicted in smoking women. If rs1136141-G/G genotype is detected, a low risk of ischemic stroke is predicted.

EFFECT: method provides new criteria for assessing the risk of ischemic stroke in smoking women being the residents of Central Russia based on genotyping of the polymorphic variant rs1136141 (G>A) of HSPA8 gene.

1 cl, 1 dwg, 1 tbl, 3 ex

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RU 2 806 497 C1

Authors

Bushueva Olga Iurevna

Polonikov Aleksei Valerevich

Dates

2023-11-01Published

2023-03-29Filed