FIELD: chemistry.
SUBSTANCE: invention relates to a compound of a pyridone derivative of formula I or its pharmaceutically acceptable salt, R or S isomer, where A is a C1-C10-heteroaryl group, which is unsubstituted or substituted with one or two substitutes selected from a group consisting of halogen group C1-C6-alkyl group, C3-C7-cycloalkyl group, C6-C12-aralkyl group, C1-C6-alkoxy group and C6-C12-aryl group; B represents O or NH; and C1-C10-heteroaryl group is selected from a group consisting of thiazolyl, benzothiazolyl, pyridyl, isoxazolyl, isquinolyl, quinolyl, benzothiadiazole, thiadiazole, pyrazolyl and pyrazinyl. Invention also relates to a pharmaceutical composition for preventing or treating cognitive disorders, wherein composition contains a pyridone derivative of formula I, its pharmaceutically acceptable salt, R or S isomer, in a therapeutically effective amount and a pharmaceutically acceptable carrier.
EFFECT: technical result is a pyridone derivative as an agonist or partial agonist of α7-nicotinic acetylcholine receptor.
6 cl, 2 tbl, 48 ex
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