METHOD OF PRODUCING BENZYL-[(3aS, 4R, 6S, 6aR)-6-HYDROXY-2, 2-DIMETHYLTETRAHYDRO-3aN-CYCLOPENTA[d][1,3]DIOXOL-4-YL]CARBAMATE AND INTERMEDIATE COMPOUNDS IN SAID METHOD Russian patent published in 2016 - IPC C07D317/44 C07B57/00 

Abstract RU 2588673 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to a method of producing benzyl-[(3aS,4R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydro-3aN-cyclopenta[d][1,3]dioxol-4-yl]carbamate of formula (VI) and to intermediate products of this method. This compound is used as an intermediate product in synthesis of a pharmaceutical preparation, for example, Tikagrelor.

EFFECT: higher output and faster process.

10 cl, 17 ex

Similar patents RU2588673C2

Title Year Author Number
METHOD FOR PREPARING (3aR, 4S, 6R, 6aS)-6-AMINO-2, 2-DIMETHYLTETRAHYDRO-3aNE-CYCLOPENTA[d][1,3]DIOXOL-4-OLE-DIBENZOYL-TARTRATE AND PRODUCTS OF SAID METHOD 2008
  • Aufdenblatten Roni
  • Bolin Martin Khans
  • Djukri Loren
  • Lindblad Ul'Rika
  • Magnusson Mattias
RU2477277C2
METHOD FOR OBTAINING [1S-[1α,2α,3β(1S*,2R*),5β]]-3-[7-[2-(3,4-DIFLUOROPHENYL)-CYCLOPROPYLAMINO]-5-(PROPYLTHIO)-3H-1,2,3-TRIAZOLO[4;5-d]PYRIMIDINE-3-YL]-5-(2-HYDROXYETHOXY)-CYCLOPENTANE-1,2-DIOL AND ITS INTERMEDIATE COMPOUNDS 2009
  • Aufdenblatten Roni
  • Bokhlin Martin Khans
  • Khellstrem Khelena
  • Jokhansson Peter V.
  • Larsson Ul'F G.
  • Reknagel' Mikaehla
  • Uehjss Andreas
RU2509082C2
RMT5 INHIBITORS 2019
  • Mashasek, Mishell
  • Vitter, Devid
  • Zhibo, Krejg
  • Khuan, Chunkhoj
  • Kavamura, Sukhei
  • Sloman, Devid, L.
  • Silipkhaivankh, Pkhieng
  • Kiros, Rajan
  • Van, Myurrej
  • Shnajder, Sebastyan
  • Jeung, Charlz, S.
  • Rojtershan, Majkl, Kh.
  • Khenderson, Timoti, Dzh.
  • Paparen, Zhan-Loran
  • Raali, Usin
  • Khyuz, Dzhonatan, M., E.
  • Sanyal, Sulagna
  • Je, Jingchun
  • Kandito, Devid, A.
  • Fajer, Patrik, S.
  • Silverman, Stiven, M.
RU2814198C2
SUBSTITUTED PURINE AND 7-DEAZAPURINE COMPOUNDS 2011
  • Olkhava Edvard Dzhejms
  • Chesuort Richard
  • Kuntts Kevin Uejn
  • Richon Viktoriya Mari
  • Pollok Roj Makfarlejn
  • Dejgl Skott Richard
RU2606514C2
COMPOUNDS AND COMPOSITIONS USED FOR TREATMENT OF NTRK-RELATED DISORDERS 2016
  • Wenglowsky Steven Mark
  • Brooijmans Natasja
  • Miduturu Chandrasekhar V.
  • Bifulco Neil
RU2744974C2
SHIP1 MODULATORS AND METHODS RELATED THERETO 2014
  • Makkenzi Llojd F.
  • Makruri Tomas B.
  • Kharvig Kertis
  • Bogutski Devid
  • Rejmond Dzheffri R.
  • Pettigryu Dzheremi D.
RU2679805C2
DERIVATIVES OF PYRROLOPYRIMIDINE USEFUL AS JAK-KINASES INHIBITORS 2012
  • Chzhan Syuetszyun
  • Dun Tsin
  • Lyu Bonyan
  • Chzhu Yaopin
  • Li Syaotao
  • Lan Tszyun
RU2618673C2
PYRIMIDINE COMPOUNDS, METHODS FOR THEIR PREPARING (VARIANTS), INTERMEDIATE SUBSTANCES (VARIANTS) AND METHODS FOR THEIR PREPARING (VARIANTS), METHOD FOR PREPARING TRIAZOLOPYRIMIDINE COMPOUNDS 2001
  • Larsson Ul'F
  • Magnusson Mattias
  • Musil' Tibor
  • Pal'Mgren Andreas
RU2295526C2
COMPOSITIONS AND METHODS FOR INHIBITING VIRAL POLYMERASE 2013
  • Kotian Pravin L.
  • Babu Yarlagadda S.
RU2654482C2
COMPOUNDS WHICH ARE ANTAGONISTS OF THE A3-ADENOSINE RECEPTOR, A METHOD FOR PREPARING THEM AND MEDICAL USE THEREOF 2017
  • Lee, Jinhwa
  • Kim, Seungyong
  • Kim, Doran
  • Ahn, Koo Hyeon
  • Lee, Gwi Bin
  • Kim, Dooseop
  • Hwang, Hyun Sook
RU2737157C2

RU 2 588 673 C2

Authors

Musil Tibor

Dates

2016-07-10Published

2012-05-11Filed