METHOD FOR OBTAINING [1S-[1α,2α,3β(1S*,2R*),5β]]-3-[7-[2-(3,4-DIFLUOROPHENYL)-CYCLOPROPYLAMINO]-5-(PROPYLTHIO)-3H-1,2,3-TRIAZOLO[4;5-d]PYRIMIDINE-3-YL]-5-(2-HYDROXYETHOXY)-CYCLOPENTANE-1,2-DIOL AND ITS INTERMEDIATE COMPOUNDS Russian patent published in 2014 - IPC C07D487/04 C07D317/44 C07D405/12 C07D405/04 

Abstract RU 2509082 C2

FIELD: biotechnologies.

SUBSTANCE: invention refers to a method for obtaining [1S-[1α,2α,3β(1S*,2R*),5β]]-3-[7-[2-(3,4-difluorophenyl)-cyclopropylamino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidine-3-yl]-5-(2-hydroxyethoxy)-cyclopentane-1,2-diol of formula (I) .

EFFECT: improving yield of the compound of the formula and its high quality when recrystallisation is not available.

5 cl, 1 tbl, 10 ex

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Authors

Aufdenblatten Roni

Bokhlin Martin Khans

Khellstrem Khelena

Jokhansson Peter V.

Larsson Ul'F G.

Reknagel' Mikaehla

Uehjss Andreas

Dates

2014-03-10Published

2009-09-08Filed