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2 591 256

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IPC

C07C317/04(2006-01-01)

C07C317/44(2006-01-01)

A61K31/10(2006-01-01)

A61P31/06(2006-01-01)

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Application

2015101008/04, 2015-01-12

(24)

Start date

2015-01-12

(22)

Actual filing date

2015-01-12

(45)

Published

2016-07-20

(72)

Inventor

Fattakhov Saitgarej GalyauvichShulaeva Marina MikhajlovnaKravchenko Marionella AnatolevnaMingaleev Danil NailevichSkornyakov Sergej NikolaevichSinyashin Oleg Geroldovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Organicheskoj I Fizicheskoj Khimii Im. A.E. Arbuzova Kazanskogo Nauchnogo Tsentra Rossijskoj Akademii Nauk

α,ω-BIS(AMIDE- AND HYDRAZIDE METHYL SULFINYL- AND SULPHONYL) ALKANES HAVING ANTI-TUBERCULOSIS ACTIVITY, AND α,ω-BIS(METHOXY CARBONYL METHYL SULFINYL- OR SULPHONYL) ALKANES FOR PRODUCTION THEREOF Russian patent published in 2016 - IPC C07C317/04 C07C317/44 A61K31/10 A61P31/06

Abstract RU 2591256 C1

FIELD: chemistry.

SUBSTANCE: invention relates to sulphur-containing dicarboxylic acids of formula (1)

wherein: X=NH₂, m=1, n=2, 3, 4, 5, 6, 7, 8, 10; X=NH₂, m=2, n=1, 2, 3, 4, 5, 6, 7, 8, 10; X=NHNH₂, m=1, n=1, 2, 3, 5, 6, 7, 8, 10; X=NHNH₂, m=2, n=1, 2, 3, 4, 5, 6, 7, 8, 10. Invention also relates to sulphur-containing dicarboxylic acids of formula (2)

wherein: m=1, n=2, 3, 4, 5, 6, 7, 8, 10; m=2, n=3, 4, 5, 6, 7, 8, 10; used for producing compounds of formula (1).

EFFECT: compounds of formula (1) have high tuberculostatic activity, including in relation to multi-drug resistant Mycobacteria strains, low toxicity and simplicity of synthesis.

3 cl, 2 tbl, 59 ex

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RU 2 591 256 C1

Authors

Fattakhov Saitgarej Galyauvich

Shulaeva Marina Mikhajlovna

Kravchenko Marionella Anatolevna

Mingaleev Danil Nailevich

Skornyakov Sergej Nikolaevich

Sinyashin Oleg Geroldovich

Dates

2016-07-20—Published

2015-01-12—Filed