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2 592 205

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(51)

IPC

G01N33/50(2006-01-01)

(21) (22)

Application

2015110822/15, 2015-03-26

(24)

Start date

2015-03-26

(22)

Actual filing date

2015-03-26

(45)

Published

2016-07-20

(72)

Inventor

Churnosov Mikhail IvanovichKirilenko Mikhail YurevichTikunova Evgeniya ViktorovnaSirotina Svetlana SergeevnaPolonikov Aleksej Valerevich

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Natsionalnyj Issledovatelskij Universitet"

METHOD FOR PREDICTION OF RISK OF POAG USING GENETIC DATA Russian patent published in 2016 - IPC G01N33/50

Abstract RU 2592205 C1

FIELD: medicine.

SUBSTANCE: invention relates to medical diagnostics and aims at predicting risk of developing primary open-angle glaucoma (POAG). In Russian individuals, natives of Central black earth region is determined age, systolic and diastolic blood pressure, presence of burdened family medical history, presence of accompanying non-infectious eye diseases, microvascular changes in conjunctiva, degree of pigmentation angle of anterior chamber, peripheral venous blood is sampled and DNA recovery, VEGF-A c.-958C>T (rs833061) gene polymorphism is analysed, after which value of discriminant values D_p and D_k are determined by formulas. In case if D_p is more than D_k, risk of POAG is predicted.

EFFECT: invention provides early diagnosis of POAG and enables to generate risk groups of this disease.

1 cl, 3 dwg, 5 ex

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RU 2 592 205 C1

Authors

Churnosov Mikhail Ivanovich

Kirilenko Mikhail Yurevich

Tikunova Evgeniya Viktorovna

Sirotina Svetlana Sergeevna

Polonikov Aleksej Valerevich

Dates

2016-07-20—Published

2015-03-26—Filed