FIELD: medical diagnostics.
SUBSTANCE: invention relates to the field of medical diagnostics and is intended to predict the risk of developing primary open-angle glaucoma (POAG) in individuals of Russian nationality born and living in the Central region of Russia. Venous blood sampling, DNA extraction from peripheral venous blood, CDKN2-AS1 gene analysis are carried out. If the AG haplotype of the haploblock rs1063192 and rs7865618 of the CDKN2-AS1 gene is detected, a high risk of developing POAG is predicted.
EFFECT: invention provides for obtaining new criteria for assessing the risk of developing POAG in unrelated individuals of Russian nationality born and living in the Central region of Russia.
1 cl, 2 dwg, 4 ex
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Authors
Dates
2022-04-26—Published
2021-10-26—Filed