2,6-DIAMINOPURINE--β--D-RIBOFURANURONAMIDE DERIVATIVES, METHOD OF PREPARING THEREOF, PHARMACEUTICAL COMPOSITION FOR SUPPRESSING ACTIVITY OF LEUKOCYTES, METHOD OF PREPARING PHARMACEUTICAL COMPOSITION, AND METHOD OF SUPPRESSING LEUKOCYTES Russian patent published in 1999 - IPC

Abstract RU 2129561 C1

FIELD: medicine. SUBSTANCE: invention describes 2,6-diaminopurine--β--D- ribofuran uronamide of formula (I): -β- and salts of compounds in which R1 is C1-3-alkyl group; R2 is C3-8- cycloalkyl group, radicals Alk1,(CHR5)m(Alk2)nZ,, or substituted C3-8- cycloalkyl, pyrrolidin-3-yl, 2-oxopyrrolidin-4-yl, piperidin-3-yl or piperidin-4-yl group; Q is oxygen atom. Compounds of formula (I) and salts thereof are useful in medicine as antiinflammatory agents, especially for treating patients suffering from inflammatory diseases and tissue damage induced by leukocytes. EFFECT: improved properties of the title compounds. 18 cl, 44 ex, 5 tbl

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RU 2 129 561 C1

Authors

Gregson Majkl

Ehjrz Berri Ehdvard

Ivan Dzhordzh Blehng

Ehllis Frehnk

Najt Dzhon

Dates

1999-04-27Published

1994-01-18Filed