FIELD: medicine; pharmacology.
SUBSTANCE: this invention describes new crystal forms of tryazol[4,5-d]pyrimidine formula I 
, composition methods and based pharmaceutical formulations. Compounds develop high efficiency as antagonist P2T, can be applied for medical prevention and treatment of arterial thrombotic complication, as well as tumour growth and extension.
EFFECT: compounds show high metabolic stability and bioavailability.
22 cl, 5 ex, 6 dwg
| Title |
Year |
Author |
Number |
| NOVEL CRYSTALLINE FORM OF TRIAZOLO(4,5-d)PYRIMIDINE |
2005 |
- Bolin Martin
- Kosgrouv Stiv
- Lassen Bo
|
RU2418802C2 |
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- Gil Sajmon
- Khardern Devid
- Ingoll Entoni
- Springtorp Brajan
- Uillis Pol
|
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2001 |
- Larsson Ul'F
- Magnusson Mattias
- Musil' Tibor
- Pal'Mgren Andreas
|
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| DERIVATIVES OF 3-H-1,2,3-TRIAZOLO-[4,5-D]-PYRIMIDINE, PHARMACEUTICAL COMPOSITION AND METHOD OF THEIR SYNTHESIS |
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- Koks Dehvid
- Ingoll Ehntoni
- Uillis Pol
|
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2009 |
- Aufdenblatten Roni
- Bokhlin Martin Khans
- Khellstrem Khelena
- Jokhansson Peter V.
- Larsson Ul'F G.
- Reknagel' Mikaehla
- Uehjss Andreas
|
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1994 |
- Gregson Majkl
- Ehjrz Berri Ehdvard
- Ivan Dzhordzh Blehng
- Ehllis Frehnk
- Najt Dzhon
|
RU2129561C1 |
| TRIAZOLO[4,5-D]PYRIMIDINE COMPOUNDS, METHODS FOR THEIR PREPARING (VARIANTS), PHARMACEUTICAL COMPOSITION |
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- Gajl Simon
- Ingoll Ehntoni
- Springtorp Brajan
- Uillis Pol
|
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2008 |
- Aufdenblatten Roni
- Bolin Martin Khans
- Djukri Loren
- Lindblad Ul'Rika
- Magnusson Mattias
|
RU2477277C2 |
| METHOD AND INTERMEDIATE COMPOUNDS FOR PREPARING LATANOPROST |
2002 |
|
RU2267480C2 |
| SALT AND POLYMORPH OF A PHENYL-PYRIMIDONE COMPOUND, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF |
2018 |
- Shen, Jingshan
- He, Yang
- Chen, Weiming
- Li, Jianfeng
- Tian, Guanghui
- Gong, Xudong
- Wang, Zhen
- Zhang, Rongxia
- Liu, Yongjian
- Jiang, Hualiang
|
RU2761213C2 |
