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2 595 380

(13)

(51)

IPC

C12N1/20(2006-01-01)

C12P7/62(2006-01-01)

C12R1/465(2006-01-01)

(21) (22)

Application

2011153811/10, 2009-02-05

(24)

Start date

2009-02-05

(22)

Actual filing date

2009-02-05

(45)

Published

2016-08-27

(72)

Inventor

Garg, Majyank, KumarGarg, SaurabkhDzhoshi, SulekkhaDzhoel, AnudzhIjer, KharishKumar, BimalKumar, Chittnalli, Ramegovda, NaveenPatale, Mukesh, BabuappaTivari, Sandzhaj

(73)

Holder

Bajokon Limitid

FERMENTATION MEDIUM FOR PRODUCING PRAVASTATIN AND METHOD OF PRODUCING PRAVASTATIN Russian patent published in 2016 - IPC C12N1/20 C12P7/62 C12R1/465

Abstract RU 2595380 C2

FIELD: biotechnology.

SUBSTANCE: group of inventions relates to biotechnology. Invention discloses fermentation medium and method for producing pravastatin. One performs incubation microorganisms Streptomyces sp. in fermentative medium containing soya bean flour, dextrose monohydrate, cotton flour, maize syrup, NaCl, antifoaming agent SAG, and water and urea or its derivative in concentration of 0.5 g/l to 3 g/l. Then compactin solution is added. Urea derivative is selected from a group comprising dimethyl urea, dimethyl urea, N-acetyl phenyl urea, isopropyl piliden urea, phenyl urea or their combinations.

EFFECT: invention increases level of compactin bioconversion into Pravastatin and reducing production time.

4 cl, 27 dwg, 16 ex

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RU 2 595 380 C2

Authors

Garg, Majyank, Kumar

Garg, Saurabkh

Dzhoshi, Sulekkha

Dzhoel, Anudzh

Ijer, Kharish

Kumar, Bimal

Kumar, Chittnalli, Ramegovda, Naveen

Patale, Mukesh, Babuappa

Tivari, Sandzhaj

Dates

2016-08-27—Published

2009-02-05—Filed