METHOD FOR PREDICTION OF INFECTIOUS COMPLICATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE Russian patent published in 2016 - IPC G01N33/53 

Abstract RU 2595853 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, specifically to pulmonology, and can be used for prediction of infectious complications of chronic obstructive pulmonary disease (COPD). For this purpose, method includes determining in blood serum concentration of cytokines: interleukin 17 (IL-17), interleukin 21 (IL-21), gamma-interferon (IFNγ) tumour necrosis factor-alpha (TNFα), then based on value of calculated value of ratio (IL-17 + IL-21) : (IFNγ + TNFα) determining risk of infectious complications. At ratio equal to or less (≤) than 3.89 standard units, favourable clinical course of COPD with a low risk of infectious complications is predicted, and at ratio equal to or greater (≥) than 3.90 standard units, unfavourable course of COPD is predicted with a high risk of infectious complications.

EFFECT: invention allows to prevent infectious complications and progression of bronchial obstruction in patients with COPD.

1 cl, 1 tbl, 3 ex

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RU 2 595 853 C1

Authors

Kalinina Elena Petrovna

Lobanova Elena Grigorevna

Novgorodtseva Tatyana Pavlovna

Antonyuk Marina Vladimirovna

Dates

2016-08-27Published

2015-08-04Filed