METHOD OF SIMULATING NON-ALCOHOLIC STEATOHEPATITIS IN RATS Russian patent published in 2016 - IPC G09B23/28 

Abstract RU 2598351 C1

FIELD: medicine; veterinary.

SUBSTANCE: invention can be used for simulation of non-alcoholic steatohepatitis. For this purpose, laboratory rats are used. Method involves introducing with animal fodder of 90 days 5 g of melted beef fat. Starting from day 60 of simulation, additionally performing intramuscular injections of tetracycline in dosage of 100 mg/kg once a day for 10 days.

EFFECT: method provides development of resistant morphofunctional changes, typical for non-alcoholic steatohepatitis, with reduced length of simulation.

1 cl, 3 tbl

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RU 2 598 351 C1

Authors

Areshidze David Aleksandrovich

Kozlova Mariya Aleksandrovna

Semin Ivan Aleksandrovich

Dates

2016-09-20Published

2015-05-25Filed