FIELD: chemistry.
SUBSTANCE: complex esters of hyaluronic acid and hydroxycinnamic acid derivatives are proposed. With that, hydroxycinnamic acid derivatives are selected from ferulic acid and caffeic acid. Method of producing esters of hyaluronic acid involves dissolving sodium salt of hyaluronic acid in formamide. With that, the said salt is introduced into the reaction in the presence of an equivalent amount of tertiary hydroxycinnamic acid derivatives with base pre-activated carbonyldiimidazole at the room temperature. Obtained viscous mass is diluted with water solution of NaCl, the reaction product is extracted by deposition of acetone followed by purification of methanol, filtration and drying in vacuum.
EFFECT: invention allows obtaining esters of hyaluronic acid and hydroxycinnamic acid derivatives used for skin protection as the compounds that reinforce elasticity with moisturizing, softening action.
15 cl, 6 dwg, 1 tbl, 9 ex
