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(19)

RU

(11)

2 599 289

(13)

C2

(51)

IPC

A61K45/00(2006-01-01)

A61K31/23(2006-01-01)

A61K31/52(2006-01-01)

A61K31/55(2006-01-01)

A61K31/47(2006-01-01)

A61K31/395(2006-01-01)

A61P43/00(2006-01-01)

(21) (22)

Application

2013156908/15, 2013-12-20

(24)

Start date

2013-12-20

(22)

Actual filing date

2013-12-20

(45)

Published

2016-10-10

(72)

Inventor

Zyuzkov Gleb NikolaevichZhdanov Vadim VadimovichDanilets Marina GrigorevnaMiroshnichenko Larisa ArkadevnaUdut Elena VladimirovnaDygaj Aleksandr Mikhajlovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Institut Farmakologii Imeni E.D. Goldberga" Sibirskogo Otdeleniya Rossijskoj Akademii Meditsinskikh Nauk Fgbu Farmakologii Imeni E.D. Goldberga" So Ramn

TISSUE REGENERATION STIMULATING AGENT Russian patent published in 2016 - IPC A61K45/00 A61K31/23 A61K31/52 A61K31/55 A61K31/47 A61K31/395 A61P43/00 

Abstract RU 2599289 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, more specifically to pharmacology, cell technologies and regenerative medicine. Task solved by this invention, is increasing of effective agents range stimulating tissue regeneration. Assigned task is solved by using as tissue regeneration stimulating agents, of pharmacological substances having direct action on PI3K-, PKB-, PKC-, NF-κB-, MAPK-, JAK/STAT, cAMP-, PKA/CREB-mediated signaling in progenitor cells.

EFFECT: proposed agents allow to efficiently stimulate regeneration of tissues impaired by pathological process, due to activation of resident (regional) progenitor cells functions by effect on intracellular signal transduction.

8 cl, 24 tbl, 7 ex

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RU 2 599 289 C2

Authors

Zyuzkov Gleb Nikolaevich

Zhdanov Vadim Vadimovich

Danilets Marina Grigorevna

Miroshnichenko Larisa Arkadevna

Udut Elena Vladimirovna

Dygaj Aleksandr Mikhajlovich

Dates

2016-10-10—Published

2013-12-20—Filed

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