IMPROVED CODED MICROCARRIERS, TEST SYSTEMS AND ANALYSIS METHODS USING THEM Russian patent published in 2016 - IPC B01L3/00 G01N33/543 G01N35/00 B01J19/00 

Abstract RU 2599304 C2

FIELD: micro-appliances.

SUBSTANCE: invention relates to coded microcarrier and, in particular, to microcarrier containing spatial element; to test system and method for conducting chemical and/or biological analysis. Coded microcarrier (2) comprises readable code for its identification. Microcarrier includes body (3) having at least one detection surface (6) for detection of chemical and/or biological reaction. Microcarrier contains therein at least one spatial element (9) that projects from body (3) and have shape, which, when coded microcarrier (2) lies on plane (10) with detection surface (6) facing to plane (10), can provide for clearance (11) between plane (10) and detection surface (6). Contact surface (14) therein, contacting with plane (10) is located at distance from detection surface (6), and maximum distance (d) between detection surface (6) and plane (10) is more than 5 % of maximum height (H) of coded microcarrier (2), preferably more than 10 %. Test system (100) comprises multiple coded microcarriers and analyzing device (101) having at least one microfluidic channel (102), having shape allowing to place multiple coded microcarriers (2). Microfluidic channel (102) has at least one wall for observation (106), through which analytical control is performed. Microfluidic channel (102) and spatial elements (9) of each microcarrier (2) have such shape, that can ensure clearance (10) between detection surface (6) and wall for observation (106) in order to allow fluid circulation in said gap (10). Disclosed method comprises using at least one coded microcarrier (2). Control over chemical and/or biological reaction therein is carried out on detection surface (6) of coded microcarrier (2).

EFFECT: providing fast quantitative analysis of analyzed drenching substance.

13 cl, 9 dwg

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RU 2 599 304 C2

Authors

Demer Nikola

Dates

2016-10-10Published

2012-02-06Filed