NEW POLYMORPHIC FORM OF A CALCIEMETRIC COMPOUND Russian patent published in 2016 - IPC C07C213/10 C07C217/74 C07C229/46 A61K31/196 A61P3/14 A61P5/18 

Abstract RU 2599789 C2

FIELD: chemistry.

SUBSTANCE: invention is related to a crystalline form {4-[(1R,3S)-3-((R)-1-naphthalene-1-YL-ethylamino) cyclopentyl] phenoxy} acetic acid, which can be used for treating, relieving symptoms or preventing the physiological disorders or diseases, associated with disturbed activity of a calcium-sensitive receptor (CaSR), such as hyperparathyroidism. Crystalline form has x-ray powder diffraction pattern, displaying characteristic peaks, expressed in angles 2θ, at approximately 8.8, 9.5, 12.3, 16.0, 18.3, 19.1 and/or 20.2 (±0.1 degrees) (its stress is the main).

EFFECT: invention is also related to a pharmaceutical compound containing the said crystalline form, and methods for preparing it.

17 cl, 12 dwg, 6 tbl, 6 ex

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RU 2 599 789 C2

Authors

Ebdrup Seren

Nilsen Kim Tronsegord

Greve Tanya Mariya

Dates

2016-10-20Published

2011-06-24Filed