METHOD OF AMINOGLYCOSIDE ANTIBIOTICS IN SODIUM ALGINATE NANO-CAPSULES PRODUCING Russian patent published in 2016 - IPC A61K31/7036 A61K47/36 A61K9/51 A61J3/07 B01J13/02 B82B3/00 

Abstract RU 2599841 C1

FIELD: medicine.

SUBSTANCE: invention relates to nanotechnology and medicine. Described is method of aminoglycoside antibiotics in sodium alginate envelope nano-capsules producing. According to method according to invention aminoglycoside antibiotic is added in portions into sodium alginate suspension in benzene, containing E472c preparation as surfactant with mass ratio of aminoglycoside antibiotic: sodium alginate of 1:1 or 1:3. Mixture is stirred, then methyl ethyl ketone is added. Obtained suspension of nano-capsules is filtered, washed with methyl ethyl ketone and dried. Process is performed within 15 minutes.

EFFECT: method according to invention provides simplification and acceleration of nano-capsules producing process in sodium alginate and increases mass output.

1 cl, 1 dwg, 7 ex

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RU 2 599 841 C1

Authors

Krolevets Aleksandr Aleksandrovich

Dates

2016-10-20Published

2015-08-24Filed