METHOD OF DETERMINING DEGREE OF HETEROPLASMY MUTATIONS OF MITOCHONDRIAL GENOME Russian patent published in 2016 - IPC G01N33/50 C12Q1/68 

Abstract RU 2600023 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine and aims at determining the degree of heteroplasmy of mitochondrial genome mutations. Polymerase chain reaction is carried out in real time, calculating the value of ΔCt, determined the coefficient of efficiency of amplification and a degree of heteroplasmy of mutations of mitochondrial genome by formula.

EFFECT: invention provides a simple and accessible for use in clinical practice method of determining heteroplasmy mutations of mitochondrial genome.

1 cl, 5 ex

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RU 2 600 023 C1

Authors

Sobenin Igor Aleksandrovich

Mitrofanov Konstantin Yurevich

Postnov Anton Yuvenalevich

Dates

2016-10-20Published

2015-12-29Filed