FIELD: medicine.
SUBSTANCE: DNA is extracted from the patient's blood, mitochondrial DNA (mtDNA) is genotyped, the degree of mtDNA heteroplasmia is determined by the m.652delG mutation. With a value above 22.5%, high genetic risk is judged.
EFFECT: increased effectiveness and accuracy of determination of predisposition to atherosclerosis, coronary artery disease and myocardial infarction.
4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR MULTIPARAMETRIC DETERMINATION OF PREDISPOSITION TO ATHEROSCLEROSIS AND ITS CLINICAL MANIFESTATIONS | 2016 |
|
RU2641571C1 |
| METHOD FOR ASSESSING GENETIC RISK OF ATHEROSCLEROSIS BASED ON DETERMINATION OF MITOCHONDRIAL GENOME VERSIONS | 2015 |
|
RU2592233C1 |
| METHOD FOR PREDICTION OF MULTIFOCAL ATHEROSCLEROTIC INVOLVEMENT | 2018 |
|
RU2704224C1 |
| METHOD FOR PREDICTION OF ATHEROSCLEROSIS DEVELOPMENT | 2018 |
|
RU2704960C1 |
| METHOD FOR LIABILITY TO DEVELOPMENT OF ATHEROSCLEROSIS IN MIDDLE-AGED MEN | 2020 |
|
RU2738975C1 |
| METHOD FOR IDENTIFYING INDIVIDUALS FOR IN-DEPTH EXAMINATION IN ISCHEMIC HEART DISEASE | 2012 |
|
RU2545420C2 |
| METHOD FOR PREDICTION OF ACUTE MYOCARDIAL ISCHEMIA OUTCOME | 2016 |
|
RU2649774C1 |
| METHOD OF DETERMINING DEGREE OF HETEROPLASMY MUTATIONS OF MITOCHONDRIAL GENOME | 2015 |
|
RU2600023C1 |
| METHOD FOR PREDICTING MULTIPLE ORGAN FAILURE AFTER HEART SURGERY PERFORMED UNDER CONDITIONS OF ARTIFICIAL BLOOD CIRCULATION | 2020 |
|
RU2753589C1 |
| METHOD FOR MOLECULAR DIAGNOSTICS OF MITOCHONDRIAL PATHOLOGIES BASED ON PYROSEQUENCING TECHNOLOGY | 2015 |
|
RU2633752C2 |
