METHOD OF TREATING CHRONIC RECURRENT ORAL ULCERATION Russian patent published in 2016 - IPC A61K31/715 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to dentistry, and can be used for treating chronic recurrent oral ulceration. Method of treating chronic recurrent oral ulceration includes clinical and biochemical examination of the patient and prescribing the drug therapy, meaning reception of sublingual tablets of sodium aminodihydro-phthalazinedione (Galavit) as per 10 days by 4 tablets and 10 days every second day in a daily dose. Additionally, presence of urogenital infection is detected using real-time polymerase chain reaction and immunological parameters of the oral fluid are examined and if the patient's urogenital infection is identified and values of local immunity factors balance coefficient exceed 4.59±0.343 and secretory immunoglobulin A concentration lower than 0.089±0.012 prescribed are the sublingual pills based on sodium aminodihydro-phthalazinedione (Galavit) for 30 days according to the schedule: 10 days - daily - 4 tablets a day, further - 10 days taking pills every second day in the same daily dose, hydroxyzine hydrochloride (Atarax) in 3 receptions by 12.5 mg in the morning and the afternoon, 25 mg in the evening for 4 weeks and intraoral applications with lanthanum triethylene trinitrate in polyhydroxy compounds (Eplan) with the duration of 20-30 minutes 3-4 times a day till complete epithelization of the injury elements.

EFFECT: using the invention enables reducing the treatment terms, reducing the epithelization terms, reducing the pain syndrome and the rate of recurrences.

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