MODIFIED BIOSENSOR FOR DETECTING INTRACELLULAR PH Russian patent published in 2016 - IPC C12Q1/68 C07H21/00 C07K14/00 

Abstract RU 2603060 C2

FIELD: biotechnologies.

SUBSTANCE: group of inventions relates to biotechnology. Group of inventions includes a nucleic acid, which encodes a fluorescent biosensor for detecting change in pH, amino acid sequence of which is shown in SEQ ID No: 4, as well as an expression cassette and eucariotic cell producing a biosensor.

EFFECT: group of inventions is aimed at biosensors for detecting change in pH in living cells, having high fluorescence brightness.

4 cl, 6 dwg, 4 ex

Similar patents RU2603060C2

Title Year Author Number
CHIMERIC PROTEIN BEING FLUORESCENT BIOSENSOR FOR SIMULTANEOUS DETECTION OF HYDROGEN PEROXIDE AND PHOSPHATIDYL INOSITOL-3,4,5-TRIPHOSPHATE, NUCLEINIC ACID CODING SUCH PROTEIN, EXPRESSION CASSETTE AND EUCARIOTIC HOST CELL 2012
  • Belousov Vsevolod Vadimovich
  • Mishina Natalija Mikhajlovna
  • Chudakov Dmitrij Mikhajlovich
RU2498996C1
ISOLATED NUCLEIC ACID CODING FLUORESCENT BIOSENSOR FOR DETECTION OF HYDROGEN PEROXIDE, EXPRESSION CASSETTE, CELL THAT PRODUCES BIOSENSOR, ISOLATED FLUORESCENT BIOSENSOR FOR DETECTION OF HYDROGEN PEROXIDE, ISOLATED NUCLEIC ACID THAT CODES FLUORESCENT BIOSENSOR, EFFICIENTLY FUSED WITH NUCLEIC ACID THAT CODES SIGNAL OF INTRACELLULAR LOCALISATION 2011
  • Bilan Dmitrij Sergeevich
  • Belousov Vsevolod Vadimovich
  • Luk'Janov Sergej Anatol'Evich
RU2493260C2
ISOLATED NUCLEIC ACID CODING FLUORESCENT BIOSENSOR, EXPRESSION CASSETTE, CELL, PRODUCING FLUORESCENT BIOSENSOR, ISOLATED FLUORESCENT BIOSENSOR 2012
  • Bilan Dmitrij Sergeevich
  • Belousov Vsevolod Vadimovich
  • Luk'Janov Sergej Anatol'Evich
RU2515903C2
NUCLEIC ACID ENCODING FRET-BASED FAR-RED BIOSENSOR FOR INTRACELLULAR CASPASE 3 ACTIVITY MEASUREMENT 2013
  • Luk'Janov Konstantin Anatol'Evich
  • Zlobovskaja Ol'Ga Anatol'Evna
RU2535981C1
RED FLUORESCENT BIOSENSOR FOR DETECTION OF HYDROGEN PEROXIDE IN LIVING CELLS 2013
  • Belousov Vsevolod Vadimovich
  • Ermakova Julija Gennadievna
  • Enikolopov Grigorij Nikolaevich
RU2535336C1
ISOLATED KillerRed PROTEIN-CODING NUCLEIC ACID (VERSIONS), ISOLATED PROTEIN (VERSIONS), EXPRESSION CASSETTE, CELL CONTAINING EXPRESSION CASSETTE 2011
  • Luk'Janov Konstantin Anatol'Evich
  • Serebrovskaja Ekaterina Olegovna
  • Luk'Janov Sergej Anatol'Evich
RU2458129C1
MODIFIED GENETICALLY CODED PHOTOSENSITIZER 2013
  • Sarkisyan Karen Sergeevich
  • Mishin Aleksandr Sergeevich
  • Lukyanov Sergej Anatolevich
RU2599443C2
ISOLATED NUCLEIC ACID, ENCODING OPERATIVELY FUSED INTRAMOLECULAR DIMER OF KillerRed PROTEIN, EXPRESSION CASSETTE, CELL, WHICH PRODUCES CHIMERIC PROTEIN AND CONTAINS EXPRESSION CASSETTE, ISOLATED CHIMERIC PROTEIN 2011
  • Luk'Janov Konstantin Anatol'Evich
  • Serebrovskaja Ekaterina Olegovna
  • Luk'Janov Sergej Anatol'Evich
RU2491342C1
BIOSENSOR FOR DETECTION OF HYDROGEN PEROXIDE IN LIVE CELLS, POSSESSING HIGHER STABILITY TO pH CHANGE 2009
  • Belousov Vsevolod Vadimovich
RU2434943C2
NOVEL FLUORESCENT PROTEINS FROM ENTACMAEA QUADRICOLOR AND METHOD OF OBTAINING SAID PROTEINS 2007
  • Luk'Janov Sergej Anatol'Evich
  • Chudakov Dmitrij Mikhajlovich
RU2395581C2

RU 2 603 060 C2

Authors

Belousov Vsevolod Vadimovich

Matlashov Mikhail Egorovich

Zagajnova Elena Vadimovna

Ermakova Julija Gennadevna

Lukjanov Sergej Anatolevich

Dates

2016-11-20Published

2014-12-25Filed