FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology. Collection of variable heavy chain and variable light chain pairs comprising, in part, germinal type protein sequences that are pre-selected for functional properties relevant to developability, wherein the collections may be used to select against any antigen using, for example, phage display.
EFFECT: proposed invention can be used in medicine.
64 cl, 73 dwg, 15 tbl, 11 ex
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