FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to experimental surgery and pathophysiology, and concerns simulating of ulcerative colitis. Colon wall ischemia is made in male rats of “Wistar” line. For this purpose at the level of descending colon part over 3 cm from the base of bladder straight branches of left colon artery and cranial rectal artery are parietally separated, ligatured and transected with accompanying veins. After that, free access to food and 1 % solution of sodium sulphate dextran is maintained for seven postoperative days.
EFFECT: method enables to obtain a model of colon ulcerative colitis close to clinical course of the disease; wherein model reproducibility is 90 %.
1 cl, 7 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| AGENT FOR THE PREVENTION AND TREATMENT OF ULCERATE COLITIS | 2017 |
|
RU2649119C1 |
| METHOD FOR INTRAPERITONEAL APPLICATION OF MEDICAL OZONE FOR TREATING ULCERATIVE COLITIS | 2021 |
|
RU2782488C1 |
| METHOD FOR ORTHOTOPIC CYTOPLASTY | 2012 |
|
RU2514530C1 |
| METHOD FOR MODELING LARGE INTESTINE DIVERTICULOSIS | 1992 |
|
RU2087943C1 |
| METHOD FOR DIAGNOSING SEVERE PSEUDOMEMBRANOUS COLITIS IN PATIENTS AFTER CORONAVIRUS INFECTION | 2022 |
|
RU2786752C1 |
| METHOD FOR MODELING PERITONITIS | 2019 |
|
RU2716482C1 |
| METHOD OF SIMULATING ADHESIVE PROCESSES IN ABDOMINAL CAVITY | 2016 |
|
RU2632538C1 |
| METHOD FOR MODELING NONSPECIFIC ULCERATIVE COLITIS CASES | 2006 |
|
RU2316055C1 |
| METHOD OF COLONIC OBSTRUCTION MODELING | 2022 |
|
RU2798407C1 |
| METHOD FOR MODELING ANAL FISSURE CASES | 2005 |
|
RU2300813C1 |
