FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine. Described is coating composition for drug eluating medical devices, which contains insoluble in water medication and at least one compound, selected from group consisting of amino acids ester compounds, which have amino acid side chain hydrophobic properties index, equal to zero or less than zero, as well as their salts.
EFFECT: composition enables to deliver medical device to target tissue for treating blood vessel damage, such as restenosis, without easy separation of drug from medical device in process of delivery.
9 cl, 5 dwg, 7 tbl, 15 ex
Title | Year | Author | Number |
---|---|---|---|
DRUG COATING LAYER | 2014 |
|
RU2648469C2 |
MEDICINAL PRODUCT WITH PARTICLE-FREE COATING RELEASING ACTIVE SUBSTANCE | 2011 |
|
RU2578422C2 |
POLYGLUTAMATE-AMINO ACID CONJUGATES AND METHODS | 2006 |
|
RU2472812C2 |
MEDICATION-DELIVERING MEDICAL DEVICE, METHOD OF OBTAINING THEREOF AND METHOD OF MEDICATION DELIVERY | 2010 |
|
RU2573045C2 |
DELIVERY OF HYDROPHOBIC ACTIVE AGENT PARTICLES | 2016 |
|
RU2733375C2 |
BALLOON CATHETER COATED WITH ANTIRESTENOSIS ACTIVE INGREDIENT AND TRANSPORT PROMOTING MOLECULAR DISPERSING AGENT | 2011 |
|
RU2543330C2 |
IMPROVED DRUG-COATED MEDICAL DEVICES, MAKING AND USING THEM | 2008 |
|
RU2471508C2 |
DEVICE FOR DELIVERY OF MEDICINAL PREPARATION, METHOD OF MANUFACTURE AND APPLICATION OF THE DEVICE | 2003 |
|
RU2316358C2 |
STENT | 2007 |
|
RU2432183C9 |
NANOPARTICLES CONTAINING CYCLODEXTRIN AND BIOLOGICALLY ACTIVE MOLECULE, AND USING THEM | 2008 |
|
RU2460518C2 |
Authors
Dates
2016-12-20—Published
2013-03-15—Filed