FIELD: pharmacology.
SUBSTANCE: group of inventions relates to the field of development of medicinal coatings. Drug coating layer has a morphological form including a plurality of elongate bodies having long axes that each crystal of a water-insoluble drug independently has on a substrate surface. Along with that, the long axes of the elongate bodies are nearly linear in shape, and the long axes of the elongate bodies form an angle in the range from 45° to 135° with respect to a substrate plane with which the long axis of the elongate body intersects. Also a medical device having a drug coating layer and a method for delivering a drug is described.
EFFECT: group of inventions provides an increase in the effect of inhibiting intravascular stenosis in the region of the lesion focus and a decrease in toxicity.
7 cl, 8 dwg, 8 ex, 3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
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|
RU2605291C2 |
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|
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|
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|
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| PHARMACEUTICAL COMPOSITIONS | 2004 |
|
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|
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| DEVICE FOR DELIVERY OF MEDICINAL PREPARATION, METHOD OF MANUFACTURE AND APPLICATION OF THE DEVICE | 2003 |
|
RU2316358C2 |
