FRACTION OF DNA-HYDROLYSE SECRETORY IMMUNOGLOBULINS OF CLASS A, WITH SELECTIVE APOPTOTIC ACTIVITY IN RELATION TO HUMAN CANCER CELLS Russian patent published in 2016 - IPC A61P35/00 C07K16/18 

Abstract RU 2605321 C1

FIELD: biochemistry.

SUBSTANCE: invention relates to biochemistry. Purposed a fraction of DNA-hydrolyse secretory immunoglobulins of class A (sIgA), having molecular weight 380 kDa, processing selective apoptotic activity in relation to human cancer cells, extracted from milk of healthy donors by affinity chromatography on protein-A-sepharose, then ion-exchange chromatography on DEAE-cellulose, then by affinity chromatography on DNA-cellulose.

EFFECT: invention enables to inhibit cancer cell growth on the way of apoptosis without inducing death of normal (non-tumorous) cells.

1 cl, 7 dwg, 1 tbl, 3 ex

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RU 2 605 321 C1

Authors

Nevinskij Georgij Aleksandrovich

Buneva Valentina Nikolaevna

Dates

2016-12-20Published

2015-07-16Filed