FIELD: biotechnology.
SUBSTANCE: fluorescent optic DNA biosensor consists of a substrate adsorbed on the substrate of a thin film of the DNA-protein complex, wherein the substrate is made of monocrystalline silicon with a surface orientation (100), a size of 18×18 mm and a thickness of 380±20 microns. The roughness of the working surface is ≤0.06 and the protein content in the thin film is from 10-15 to 10-9 mol/l.
EFFECT: development of a fluorescent optic DNA-biosensor designed for multiple use without a loss of sensitivity, particularly, in the determination of protein molecules in small concentrations.
3 tbl
| Title |
Year |
Author |
Number |
| FLUORESCENT OPTICAL DNA SENSOR |
2018 |
- Butusov Leonid Alekseevich
- Kurilkin Vladimir Vasilevich
- Nagovitsyn Ilya Anatolevich
- Chudinova Galina Konstantinovna
|
RU2684276C1 |
| MODIFIED BIOSENSOR FOR DETECTING INTRACELLULAR PH |
2014 |
- Belousov Vsevolod Vadimovich
- Matlashov Mikhail Egorovich
- Zagajnova Elena Vadimovna
- Ermakova Julija Gennadevna
- Lukjanov Sergej Anatolevich
|
RU2603060C2 |
| RED FLUORESCENT BIOSENSOR FOR DETECTION OF HYDROGEN PEROXIDE IN LIVING CELLS |
2013 |
- Belousov Vsevolod Vadimovich
- Ermakova Julija Gennadievna
- Enikolopov Grigorij Nikolaevich
|
RU2535336C1 |
| BIOSENSOR FOR DETECTION OF HYDROGEN PEROXIDE IN LIVE CELLS, POSSESSING HIGHER STABILITY TO pH CHANGE |
2009 |
- Belousov Vsevolod Vadimovich
|
RU2434943C2 |
| ISOLATED NUCLEIC ACID CODING FLUORESCENT BIOSENSOR, EXPRESSION CASSETTE, CELL, PRODUCING FLUORESCENT BIOSENSOR, ISOLATED FLUORESCENT BIOSENSOR |
2012 |
- Bilan Dmitrij Sergeevich
- Belousov Vsevolod Vadimovich
- Luk'Janov Sergej Anatol'Evich
|
RU2515903C2 |
| ISOLATED NUCLEIC ACID CODING FLUORESCENT BIOSENSOR FOR DETECTION OF HYDROGEN PEROXIDE, EXPRESSION CASSETTE, CELL THAT PRODUCES BIOSENSOR, ISOLATED FLUORESCENT BIOSENSOR FOR DETECTION OF HYDROGEN PEROXIDE, ISOLATED NUCLEIC ACID THAT CODES FLUORESCENT BIOSENSOR, EFFICIENTLY FUSED WITH NUCLEIC ACID THAT CODES SIGNAL OF INTRACELLULAR LOCALISATION |
2011 |
- Bilan Dmitrij Sergeevich
- Belousov Vsevolod Vadimovich
- Luk'Janov Sergej Anatol'Evich
|
RU2493260C2 |
| NUCLEIC ACID ENCODING FRET-BASED FAR-RED BIOSENSOR FOR INTRACELLULAR CASPASE 3 ACTIVITY MEASUREMENT |
2013 |
- Luk'Janov Konstantin Anatol'Evich
- Zlobovskaja Ol'Ga Anatol'Evna
|
RU2535981C1 |
| METHOD OF CREATING REGENERABLE BIOSENSOR BASED ON PHOTONIC CRYSTAL COMPLEX WITH AFFINITY MOLECULES |
2015 |
- Dovzhenko Dmitrij Sergeevich
- Bilan Regina Stanislavovna
- Samokhvalov Pavel Sergeevich
- Vokhmintsev Kirill Vladimirovich
- Sukhanova Alena Vladimirovna
- Nabiev Igor Rufailovich
|
RU2618606C1 |
| CHIMERIC PROTEIN BEING FLUORESCENT BIOSENSOR FOR SIMULTANEOUS DETECTION OF HYDROGEN PEROXIDE AND PHOSPHATIDYL INOSITOL-3,4,5-TRIPHOSPHATE, NUCLEINIC ACID CODING SUCH PROTEIN, EXPRESSION CASSETTE AND EUCARIOTIC HOST CELL |
2012 |
- Belousov Vsevolod Vadimovich
- Mishina Natalija Mikhajlovna
- Chudakov Dmitrij Mikhajlovich
|
RU2498996C1 |
| METHOD OF PRODUCING A BIOLOGICAL SENSOR BASED ON GRAPHENE OXIDE AND A BIOLOGICAL SENSOR ON A FLEXIBLE SUBSTRATE |
2018 |
- Komarov Ivan Aleksandrovich
- Struchkov Nikolaj Sergeevich
- Antipova Olga Mikhajlovna
- Kalinnikov Aleksandr Nikolaevich
- Nelyub Vladimir Aleksandrovich
- Borodulin Aleksej Sergeevich
|
RU2697701C1 |
