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2 617 643

(13)

(51)

IPC

C07D471/04(2006-01-01)

C07D215/48(2006-01-01)

C07D513/04(2006-01-01)

A61K31/4375(2006-01-01)

A61P35/00(2006-01-01)

A61K31/12(2006-01-01)

A61P31/18(2006-01-01)

A61P11/06(2006-01-01)

(21) (22)

Application

2013154416, 2011-09-02

(24)

Start date

2011-09-02

(22)

Actual filing date

2011-09-02

(45)

Published

2017-04-25

(72)

Inventor

Bejr Kennet V.Baumajster TimmBakmelter Aleksandr Dzh.Klodfelter Karl Kh.Khan BinsunKuntts Dzhudit D.Lin TszyanRejnolds Dominik Dzh.Smit Chejz K.Van ChzhungoChzhen Syaochzhan

(73)

Holder

Forma Tiem, Elelsi

NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITING NAMPT Russian patent published in 2017 - IPC C07D471/04 C07D215/48 C07D513/04 A61K31/4375 A61P35/00 A61K31/12 A61P31/18 A61P11/06

Abstract RU 2617643 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to compounds of formula II:

EFFECT: novel compounds of formula II are obtained, which can be used in method of inhibiting nicotinamide-phosphoribosyltransferase "NAMPT", as well as pharmaceutical compositions based thereon.

17 cl, 3 tbl, 11 ex

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RU 2 617 643 C2

Authors

Bejr Kennet V.

Baumajster Timm

Bakmelter Aleksandr Dzh.

Klodfelter Karl Kh.

Khan Binsun

Kuntts Dzhudit D.

Lin Tszyan

Rejnolds Dominik Dzh.

Smit Chejz K.

Van Chzhungo

Chzhen Syaochzhan

Dates

2017-04-25—Published

2011-09-02—Filed