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(19)

(11)

2 617 678

(13)

(51)

IPC

C07D401/12(2006-01-01)

C07D403/12(2006-01-01)

C07D403/14(2006-01-01)

C07D405/12(2006-01-01)

C07D405/14(2006-01-01)

C07D409/12(2006-01-01)

C07D413/12(2006-01-01)

A61K31/4155(2006-01-01)

A61K31/4178(2006-01-01)

A61K31/454(2006-01-01)

A61K31/5377(2006-01-01)

A61P3/10(2006-01-01)

(21) (22)

Application

2014112048, 2012-08-30

(24)

Start date

2012-08-30

(22)

Actual filing date

2012-08-30

(45)

Published

2017-04-26

(72)

Inventor

Miura TomoyaOgosi EsukeUeyama KadzukhitoMotoda DajIvayama TosikhikoSudzava KojtiNagamori KhironobuUeno KhirosiTakakhasi AkikhikoSugimoto Kadzuyuki

(73)

Holder

Dzhapan Tobakko Ink.

PYRAZOLE COMPOUND AND ITS PHARMACEUTICAL USE Russian patent published in 2017 - IPC C07D401/12 C07D403/12 C07D403/14 C07D405/12 C07D405/14 C07D409/12 C07D413/12 A61K31/4155 A61K31/4178 A61K31/454 A61K31/5377 A61P3/10

Abstract RU 2617678 C2

FIELD: medicine, pharmacy.

SUBSTANCE: invention refers to a compound of general formula

or pharmaceutically acceptable salt thereof. In formula (I) Cy represents phenyl, C3-8 cycloalkyl or C3-8cycloalkenyl , Cya isa heterocyclic group with the structure given in the invention formula,R^1a andR^2b are groups defined in the formula. The objects of invention are also the pharmaceutical composition and the agent based on formula (I) compound, the method of diabetes treatment and prevention and compound application.

EFFECT: invention is SGLT1 inhibitor and can be used to treat or prevent diabetes.

24 cl, 4 tbl, 605 ex

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RU 2 617 678 C2

Authors

Miura Tomoya

Ogosi Esuke

Ueyama Kadzukhito

Motoda Daj

Ivayama Tosikhiko

Sudzava Kojti

Nagamori Khironobu

Ueno Khirosi

Takakhasi Akikhiko

Sugimoto Kadzuyuki

Dates

2017-04-26—Published

2012-08-30—Filed